Status:
ReviewerMember since: 2022
Organization: UPenn
Really stable, save time and effort.
Application Area: ChiP-seq
"This kit can remove some small primer dimers, faster and easier than AMPxp beads or beads selection. Beads are expensive, if you want to get best results, beads take time."
Status:
ReviewerMember since: 2019
Organization: University of Colorado Anschutz Medical Campus
Quick and easy
Application Area:ChIP-qPCR
"Really easy to use and more affordable than other brands."
Status:
ReviewerMember since: 2019
Organization: University of Iowa
Best for ChIPed DNA Clean Up.
Application Area:ChIPseq samples
"Have not seen a better or equivalent product to clean up my reverse cross-linked chromatin immunoprecipitated DNA sample. In spite of the presence of 1% SDS, NaHCO3, DTT & proteinase K in the samples, it effectively cleans up the precious little quantity of my ChIPed DNA without any hassles. There is also flexibility in the volume in which I can elute my samples. I find that the ChIPed DNA sample purified using this kit is highly amenable for ChIPseq library preparation downstream."
Status:
ReviewerMember since: 2021
Organization: Pro Yard Services
Great results, simple-to-use and effective kit.
Application Area:DNA purification
"This kit is very straightforward and easy to use, providing high-quality DNA for downstream applications. I particularly like the versatility in terms of options for different starting material, and the minimal number of spin steps required compared to some similar kits."
Status:
ReviewerMember since: 2020
Organization: University of Arkansas for Medical Sciences
A cost-efficient, quality product.
Application Area:Molecular biology/cloning
"My lab recently switched to using the Zymo Clean and Concentrator for our cloning projects. This kit is easy to use and actually gives you the appropriate amount of buffer for the number of columns included. Protocol is straightforward and the yield is impressive for the cost."
Status:
ReviewerMember since: 2019
Organization: Harvard University
Great results!
Application Area:Used for ChIP-seq experiment
"Great product! The results are highly reproducible, ease to use. I recommend this for any ChIP seq experiment."
Status:
ReviewerMember since: 2019
Organization: Amherst College
This kit is a simple and straightforward way of obtaining ChIP DNA.
Application Area:Purification of DNA after chromatin cross-linking and pulldown
"This DNA Clean and Concentrator kit is easy to use, which makes processing large batches of samples more efficient. The kit is pretty good at ridding contaminants from the samples whilst keeping relatively high yield of DNA."
Status:
ReviewerMember since: 2019
Organization: BioLegend Inc
Great results.
Application Area:Epigenetics
"Using this product to clean DNA after ChIP assay. Protocol is easy to follow, few steps, and DNA is ready for qPCR."
Status:
ReviewerMember since: 2019
Organization: Johns Hopkins School of Public Health
Great results.
Application Area:PCR product purification
"Easy to use and high yield of DNA/RNA. Recommend to purify PCR products."
Status:
ReviewerMember since: 2019
Organization: Uniklinik Freiburg
Great!
Application Area:ChIP-Seq and ATAC-Seq cleanup
"Zymo kits are very easy to use and it gives high quality and quantity of ChIP or ATAC DNA for downstream sequencing."
Status:
ReviewerMember since: 2016
Organization: IBiS
Great results and easy to use
Application Area:ChIP DNA purification
"Ideal solution for DNA purification from chip applications. Straightforward workflow and room temperature storage. Very useful for other applications involving DNA purification."
Status:
ReviewerMember since: 2016
Organization: Centro de Cana - IAC
Great results
Application Area:ChIP in plants
"Works better than others kit, with a great yield. Quality is also something to consider when use this kit"
The Chromatin Immunoprecipitation (ChIP) DNA Clean & Concentrator™ provides a hassle-free method for the rapid purification and concentration of high quality DNA from any step in a standard ChIP protocol.
This includes samples that have undergone reverse cross-linking, Proteinase K or RNase A digestion, mechanical or nuclease-mediated DNA shearing, and samples eluted from chromatin-antibody-bead complexes. The specially formulated ChIP DNA Binding Buffer promotes DNA adsorption to the column in the presence of detergents, antibodies, and proteinases that are often used for ChIP.
This kit may be applied to any routine ChIP procedure to determine DNA concentration of samples that have undergone reverse cross-linking following DNA shearing. It can also be used for the removal of TES, 0.1M NaHCO3 and 1% SDS from DNA eluted from chromatin-antibody-bead complexes and can be used to purify DNA from buffers containing up to 1% SDS or 5% NP-40, Tween-20, Triton X-100 or Sarkosyl.