The global shortage of helium has forced laboratories
worldwide to consider the viability of alternative carrier gases for their gas chromatography/mass
spectrometry (GC/MS) analyses.
Hydrogen is one promising alternative that is both
renewable and low cost. However, despite its proven success across many GC/MS applications, the use of
hydrogen comes with persisting concerns that have hindered its implementation in many labs. These include the:
The below hub provides you with all the resources needed to help simplify the switch from helium to hydrogen carrier gas, outlining how Agilent Technologies is well positioned to address this daunting transition with its portfolio of products, consumables, and services.
Converting to alternative carrier gases is not always convenient or
even possible – including high-sensitivity or regulated methods. In these cases, helium conservation can be
pursued. Configuring your GC systems with a programmable helium conservation module can significantly reduce
your helium consumption. The module promises to provide better control of laboratory operating expenses,
less workflow disruption, greater reliability, and more.
Use this tool to determine how much you can save when
you reduce your helium consumption using Agilent Gas Saver, with or without an optional helium conservation
module.
For methods that allow for more flexibility, GC users can consider alternative carrier
gases. The HydroInert source for hydrogen carrier gas has been designed to improve chromatographic
efficiencies with hydrogen by minimizing unwanted in-source reactions, preserving spectral fidelity for
confident library matches, and allowing consistent use of multiple reaction monitoring transitions that were
developed using helium.
Watch this animation
to find out how to make a seamless transition to hydrogen carrier gas, and explore the resources
below to gain insight into whether the HydroInert is the right fit for your GC applications:
With proven reliability and analytical sensitivity, even for complex matrices, GC/MS solutions from Agilent Technologies continue to push the boundaries of innovation, and the Agilent 5977C single quadrupole GC/MS and 7000E Triple Quadrupole GC/MS are no exception. These workhorse instruments are compatible with the new HydroInert source, enabling researchers to get the highest quality results with hydrogen carrier gas across a wide range of industry applications. Explore below for more information on how these systems can aid throughput and sample turnaround time for your applications.
The 5977A GC/MSD, 5977B GC/MSD, 7000C GC/MS, and 7000D GC/MS are also compatible with the HydroInert source.
If you are looking to switch your carrier gas from helium to hydrogen, there are many things that need to be considered, including new filters, a different cleaning regime, new column dimensions, and re-validated methods. The good news is Agilent Crosslab Services are positioned to help you with all of this, and beyond. From start-up services, financial solutions, and method development and transfer, the team’s expertise can provide you with everything needed to get you started and make your measurements more accurate, sustainable, and cost-efficient.
While helium is always the ideal choice of carrier gas for GC/MS analysis, its high
price and reoccurring shortages have increased demand for applications using hydrogen instead. Researchers
have seen success in several real-world analyses – including semi-volatile organic compounds (SVOCs), volatile
organic compounds (VOCs), and polycyclic aromatic hydrocarbons (PAHs) – and this list of applications is
expanding with the increased use of hydrogen gas as an alternative.
Explore the resources
below that outline several successful applications using hydrogen:
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