Products & ReviewDrug discovery > Drug Manufacturing
Avanti® Polar Lipids n-dodecyl-β-D-maltoside (DDM)
Merck KGaA, Darmstadt, Germany850520PAvailable: ,Western Europe,Asia,Eastern Europe,South Central America,Caribbean,Australia Oceania,Middle East,Africa,Other
n-dodecyl-ß-D-maltopyranoside, powder
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DDM is the most widely used detergent for the isolation and purification of GPCR’s. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form.
Packaging
- 125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850520P-25g)
- 20 mL Clear Glass Screw Cap Vial (850520P-1g)
- 30 mL Amber Wide Mouth Screw Cap Glass Bottle (850520P-5g)
