Celloger®, Automated Live Cell Imaging System from Curiosis

For COS7 cell research, the Z-stacking function was a strong feature, allowing the acquisition of images at multiple focal planes and combining them to generate enhanced 2D images with improved depth information. The image stitching function was also valuable, facilitating the analysis of large cell populations by merging multiple images into a single comprehensive view.

Review Date: 16 Apr 2025 | CURIOSIS

In conjunctiva cell research, compatibility with various culture vessels was one of the most appreciated features. The system supported flasks, dishes, and well plates, allowing for flexible experimental setups. The user-friendly software made it easy to track cell confluency, monitor growth curves, and perform data analysis. The time-lapse video function was especially useful for visualizing dynamic cellular changes over time, making it an excellent tool for cell behavior analysis.

Review Date: 16 Apr 2025 | CURIOSIS

One of the most satisfying aspects of using Celloger® Mini Plus for pterygium cell research was its real-time monitoring capability. It allowed continuous observation of cell growth and changes without disturbing the culture environment, ensuring stable data acquisition. Additionally, the multi-position imaging function enabled the simultaneous analysis of multiple samples, significantly improving experimental efficiency. The autofocus function was also highly reliable, providing consistently sharp images without losing focus.

Review Date: 16 Apr 2025 | CURIOSIS

Easy to use, quick running time. Providing free analysis software would be beneficial.

Review Date: 16 Apr 2025 | CURIOSIS

The device is highly optimized for 2D cell imaging and, while originally designed for this purpose, it also demonstrated promising capabilities in imaging organoids with 3D structures. 1. High resolution and efficient imaging intervals The system enabled detailed observation of cellular structures with high resolution. Even when using multiple fluorescence channels, live imaging was possible at intervals as short as 30 minutes, which was extremely useful for time-lapse experiments. 2. Stability during imaging Imaging remained stable even when the media was changed or the plate was temporarily moved during the experiment. The transitions were also captured naturally in the resulting video. 3. Natural imaging of organoid growth Although there were some limitations, it was still possible to acquire relatively natural organoid growth images when specific organoids were properly targeted. This allowed us to collect data that effectively aligned with our research objectives.

Review Date: 16 Apr 2025 | CURIOSIS

It was easy to observe changes in both cells and GFP expression over time during the culture period.

Review Date: 16 Apr 2025 | CURIOSIS

In terms of performance, the system was very effective for checking transfection efficiency and expression levels in real time. However, the option to use higher magnification would be a valuable improvement.

Review Date: 16 Apr 2025 | CURIOSIS

It was very helpful to monitor the growth and wound healing capabilities of cells in real time. The automated time-lapse imaging system was also convenient and easy to use.

Review Date: 16 Apr 2025 | CURIOSIS

Using this system, the fluorescence (GFP) is clearly visible in the images without the need for post-processing. It offers the convenience of setting the center position for all wells at once.

Review Date: 21 Oct 2024 | CURIOSIS

Real-time measurement of both bright field and fluorescence is possible inside the incubator. It is highly advantageous that consecutive images can be captured at set positions and later compiled into a video.

Review Date: 21 Oct 2024 | CURIOSIS