Status:
ReviewerMember since: 2022
Organization: Enara Bio
User-friendly image analysis tool!
Application Area: Quantification of Markers (IHC and RNAscope)
"HALO Image analysis is a great tool, user-friendly and truly complementary to the day to day image analysis. Nuclei segmentation within HALO image analysis requires improvement in order to use it to its full potential and obtaining HALO AI just to access a better nuclei segmentation is currently too costly."
Status:
ReviewerMember since: 2021
Organization: IREC (UCLouvain)
Quick to learn and great results!
Application Area:Analysis of immunofluorescence images from melanoma samples
"The platform is very easy to use and quick to learn when you are new. I am very happy with the work that I have been able to do using Halo and the data that I have been able to have from my images. The people working in Indica labs are wonderful and always offer help. I would like to give a special thanks to Ghislaine Lioux. She has helped me numerous times and showed me lots of techniques when using Halo. I wouldn't have been able to achieve the amazing work without her help."
Status:
ReviewerMember since: 2022
Organization: University of Oxford
My research depends on it.
Application Area:Cell ecology analysis in colorectal tumours
"HALO is just simply fabulous! Easy to use, and absolutely amazing at phenotyping cells. I’m interested in immune, stroma, and epithelial populations and HALO is perfect for them all. Well worth the price. I just love it!"
Status:
ReviewerMember since: 2022
Organization: University of Exeter
Great Product! Even better service/support! Exciting to watch our data roll in!
Application Area:Antigentic intensity and Spatial studies in FFPE pancreatic tissue
"Halo has been a game-changer for our lab. In addition to the (verifiable) accuracy of the data that we can now gather with speed and ease - there are now new layers of nuance to our questions that would have previously been impossible: whole section tissue and cellular segmentation, multiplex phenotyping, spatial relationships plotted within the software that allows for quick hypothesis testing and then the ability to build layers of data to answer multiple questions from our rare tissue. Even more impressive is the after-sales care: Every time we have a question or hit a barrier, the team responds quickly and creatively. Recently they have even offered to write a small algorithm that will make our studies even easier to run. I cannot fault them. Whatever our Halo, or Halo-data, needs are - whether it's associated with the applications specialists or the tech gurus - we are never left hanging. Truly (and surprisingly) still good after 4 years of a relationship. They will have your back! It isn't an inconsiderable amount to pay out - but the fact that we went from one HALO seat - to 2 HALO seats, one with AI, and now have just upgraded to another AI and with both machines are always busy we are considering HALO Link - says its worth every dime!"
Status:
ReviewerMember since: 2022
Organization: Roche Glycart
A must-have!
Application Area:Immuno-oncology
"A great and user-friendly image analysis software for tissue segmentation, quantification and spatial analysis."
Status:
ReviewerMember since: 2022
Organization: Ludwig-Maximilians-University Munich
Great results and intuitive workflow!
Application Area:Hematopathology
"The resources (tutorial videos e.g.) on the website were really helpful to learn how to get the best out of every module. Once you got familiar with the use, the platform is intuitive and the workflow works really well. If we encounter any kind of problem, we can always get in touch and get excellent and prompt help to solve the issue."
Status:
ReviewerMember since: 2022
Organization: NIFDC
Great instrument!
Application Area:Area of tissues, immunohistochemistry analysis
"I can get a high quality result, and it is easy to use!"
Status:
ReviewerMember since: 2022
Organization: University of Palermo, Tumor Immunology Laboratory
HALO has become a fundamental tool in our research activity.
Application Area:Analysis of cell populations and spatial interactions within tissues
"Our Lab (Tumor Immunology Laboratory, University of Palermo) investigates immune responses in cancer. We adopted several tools for quantitative assessment of immunolabeling with good results. HALO offers high-quality cell segmentation and allows accurate analysis of both brighfield and fluorescence-based microphotographs or slide scans. The possibility to easily extract cell features integrating spatial information enables detailed spatial interaction analyses."
Status:
ReviewerMember since: 2021
Organization: Sorbonne Université
A software making all digital pathology analysis easier, and a great support team
Application Area:Onco-immunology: characterization of the immune microenvironment in colorectal precancerous lesiosn
"HALO and HALO AI have both been a big improvement for our image analysis. Being able to work on the whole slide and to develop artificial intelligence based tissue and nuclei classifier have been very useful for my research and made me gain a lot of time. In addition to the very complete software, the support team is very reactive and enjoyable to work with."
Status:
ReviewerMember since: 2022
Organization: Novartis Pharma AG
Great results - easy to use
Application Area:Analyze metabolites in tissue sampples
"I am very satisfied with the effectiveness of the products and service for my applications. The software is super easy to use and I achieve highest quality and reproducible results. The after sales care is of high value and the application specialists are top."
Status:
ReviewerMember since: 2022
Organization: Cordeliers Research Center
Excellent results, easy to use and flexible. A must-have for my work!
Application Area:Cancerology
"Easy-to-use software, interactive and well-designed. Halo software is a must-have for our research for several years. Frequent update give more and more possibility to analyze our images. And let's not forget the incredible work and reactivity of all the people in indica labs helping us when we have some trouble to optimize our algorithm. They saved us a lot of time with at a speed I have never seen elsewhere!"
Status:
ReviewerMember since: 2022
Organization: UCLA
HALO is a user-friendly & powerful tool for image analysis w/ great technical support
Application Area:Analysis of multiplex fluorescent immunohistochemically stained tumor tissue images with 3+ markers.
"HALO is extremely straight forward and easy to use. Great and useful features include: 1. The real-time tuning tool to allow a live view of the effects of various analysis parameters for easy optimization. 2. Annotation tools make it easy to select regions of interest. 3. The ability to perform batch analysis on many images at once. 4. Useful and handy multi-panel figure maker that makes it easy for publication."
Status:
ReviewerMember since: 2022
Organization: Fudan University Shanghai Cancer Center
Great results, can't live without this instrument!
Application Area:Analyse cell compenents in tissue samples
"Advantage: 1. Batch export, diversified export formats 2. As long as the training is in place, the analysis results are very accurate, the interface operation is very friendly, and the annotation effect is also very good in similar slices Suggestions for Improvement: 1. The module effect of serial slice registration is not very good, it can be further developed 2. It would be better if the exported annotation file could be compatible with other software such as qupath 3. The app is too expensive, I hope to have a free web version, which is convenient for viewing the results and exporting data on a personal computer 4. Considering the large number of users in China, it is recommended to enable the Chinese interface"
Status:
ReviewerMember since: 2022
Organization: Roche
Great
Application Area:Develop digital pathology on tumor tissues.
"Halo is a good software for image analysis. The performance of the non-AI modules are out of my expectation. The detection rate can be around 80% after the modification. I believe Halo AI will be better on performance and easier to use for some analysis. By the way, the local engineer is very patient and professional."
Status:
ReviewerMember since: 2022
Organization: Crown Bioscience
Excellent! Looking forward to new features!
Application Area:Cancer biology and immuno-oncology
"HALO image analysis software is a user-friendly, precise and high quality image analysis tool. It is greatly improves the working efficiency of our digital pathology research and service."
Status:
ReviewerMember since: 2022
Organization: UNMC
Great product and results. Use halo for ihc analyis almost daily.
Application Area:Analysis of various proteins by cellular compartment on ihc stain PCa tissue samples
"It’s easy to use and a great product. Overall very happy. There are always areas to improve and functions that can be added, despite this halo works extremely well for our needs."
Status:
ReviewerMember since: 2022
Organization: UCSF
Could not survive without this software
Application Area:RNA-ISH, MIBI, immunofluorescence
"HALO is user-friendly, and invaluable for quantitation of multi-omics imaging data (MIBI, CODEX/Akoya multiplex stains, RNA-ISH/RNAscope). Cell segmentation, quantitation of tissue microarray data, aligning serial images, exporting quantitative data and .fcs files, it is incredible. The support team is incredibly responsive and collaborative. HALO is a bit expensive, but it has been completely worth it for us, and it was a worthwhile investment. Highly recommend a detailed demo and purchasing this software if you are interested in quantitative data from tissue multi-omics."
Status:
ReviewerMember since: 2017
Organization: University of Oklahoma Health Sciences Center
Excellent replacement for older immunohistochemistry analysis software
Application Area:Immunohistochemistry tissue analysis
"The software is modular and can be run on a server. This helps to increase the analysis power and while reducing the hardware requirement to do the analysis from individual's side. It accepts multiple image formats for analysis which is a plus. The representatives were professional and helped in setting up more modules with ease. Since we have used other software, migrating to this one was easy and has few more analysis set up which was useful and increased its value among our researchers."
Status:
ReviewerMember since: 2022
Organization: Tulane National Primate Research Center
Buyer/User of 4 years, no regrets, would purchase again
Application Area:Digital Image Analysis
"We use HALO, HALO AI, and HALO link for our Molecular Pathology Core Lab and as our primary viewing software for our Anatomic Pathology Core. As a pathologist I find HALO's user interface to be intuitive and easy to use. I also find the annotation tools to be very helpful with repetitive and often tedious task of drawing regions of interests and identifying training regions for AI algorithm development. The Indica lab support team is very responsive to any calls or requests for support. Large program packages (group licenses with 10+ modules) are expensive and similar analytical capabilities can likely be acquired for less money. However, if you can afford it, I would highly recommend this software because of how easy to use it is and how well its supported. In my opinion ease of use is paramount for any lab with a high workload."
Status:
ReviewerMember since: 2019
Organization: Fred Hutch Cancer Center
Highly recommend.
Application Area:Evaluate the tumor microenvironment
"I work mostly with multiplex immunohistochemistry images evaluating the tumor microenvironment with a focus on tumor infiltration and cell-cell interactions. I've used several image analysis softwares over the years, but I continue to use HALO because it is easy to use yet very powerful. I started using HALO back when Indica Labs was a much smaller company and before they launched HALO Link (which I also like). Although they've grown substantially, they continue to try to provide great customer service and are always working to improve their product. No technology is perfect, but they appear to be passionate about getting past the hurdles of image analysis and to expand the functionality of the software while keeping the learning curve reasonable. I put 4/5 for Ease of Use due more to some functionality improvements that are needed."
Status:
ReviewerMember since: 2019
Organization: Immunocore
Amazing software and service.
Application Area:Image analysis of various staining using Halo software
"Indica labs is of great support when using Halo. Their customer service is really great. Halo is a very user friendly software, but the technical support is also what makes it the best digital pathology software on the market. they are always open to any suggestion and the response time is usually very short."
Status:
ReviewerMember since: 2019
Organization: Bristol-Myers Squibb
We use HALO & HALO-Link daily to coordinate studies for our analysts and pathologists.
Application Area:Immuno-oncology Research
"HALO is a whole-slide image analysis platform that is designed to work how pathologists classify & score images using a microscope. It uses a set of tools that are very familiar to anyone who has used any type of image viewing/editing program at home. It can be learned in a day to analyze brightfield & fluorescent whole slide images and TMAs. There are sophisticated tools to analyze tissues labeled by chromogenic and fluorescent IHC, RNAScope, FISH & ISH. HALO may be installed on stand-alone workstations or cloud services such as AWS. File sharing through HALO-Link lets user access studies through a simple web-interface sharing a common database. HALO AI allows any user to developing sophisticated AI based tissue classification without the need for external programs or expensive computing hardware."
Status:
ReviewerMember since: 2019
Organization: Molecular Phenotyping & Imaging Core (MPIC) Facility
Stellar support team and next level research capabilities.
Application Area:Localize and quantify cellular proteins and RNA sequences in tissues samples and tissue microarrays
"The HALO Image Analysis Platform is a complete game changer in research. Being able to analyze our digitalized tissue slides and TMA slides in order to extract cell counts & cell types based on Immunohistochemistry (IHC) & In situ hybridization (ISH; CISH & FISH) staining allows us to better & more reliably determine the effectiveness of drugs as well as further understand diseases & disease progression. Getting good at using HALO takes training, practice and WebEx assistance from Indica Labs, but once you're up an running, there's no stopping the possibilities. Pairing up this revolutionary technology with a stellar service from the Indica Labs support team that has provided us guidance, usage ideas as well as listening to the customers requests with regards to the regular software updates, makes this platform near unbeatable."
Status:
ReviewerMember since: 2019
Organization: AstraZeneca
For the Pathologist HALO is by far the best digital image analysis platform available.
Application Area:Digital image analysis of immuno-oncology clinical and preclinical samples
"As a Pathologist specializing in digital image analysis, I have had the opportunity to use several different digital image analysis platforms. Indica Labs' HALO is by far the most accurate, versatile and user friendly digital image analysis platform that I have used. Literally within 10-15 minutes of "tuning" one of their "out of the box" detection algorithms, I can perform image analysis for most simple immunohistochemical markers. The workflow is simple, with sacanned images being imported directly into HALO with or without annotations for analysis. This even allows for remote use when working off site. The customer support is AMAZING and I routinely get same day or next day help from the technical support reps. HALO is a must have for any pathologist or scientist involved in quantifying immunohistochemical stains. In addition the HALO AI module is extremely easy to use. Within 20 minutes I was able to set up AI detection of tumor vs. normal tissue, as well as tumor epithelium vs. stroma. HALO provides everything one needs for quantification of IHC for clinical and pre-clinical studies (of course with supervision of a pathologist). Best of all: it is fun, like a video game for Pathologists! "
Status:
ReviewerMember since: 2019
Organization: AstraZeneca
Excellent tool, fast, user friendly, powerful.
Application Area:Spatial analysis of multiplex immunofluorescent pathology images
"I am almost completely satisfied with the HALO image analysis platform. The main areas of improvement would be in cell segmentation using membrane markers and in data analysis after datafication of the slide. My principle bottleneck is in creating actionable insight from the multiple reported parameters. I think that Indica's experience with AI and multiplex data generation positions you well to exploit the current need in the marketplace. One more thing - phenotyping manually by thresholding with no morphology/cell size, neighbor information is good but if I had a magic wand, then phenotyping would be a full suite of tools with spatial, multimarker, and morphological features that could be weighted from 0 to 1 in a machine learning classifier model."
Status:
ReviewerMember since: 2019
Organization: University Health Network, Advanced Optical Microscopy Facility
Halo is the simply the best whole-slide analysis software available.
Application Area:Multiple cancer, neuroscience, and cardiac applications in a core facility
"Halo is simply the best whole-slide analysis software available. We have a large core facility, scanning over 15,000 brightfield and 2,000 fluorescence slides per year (plus many confocal microscopes, etc.). For whole-slide analysis, we formerly used Genie (from Aperio), and InForm (from Perkin Elmer), and we have collaborators using Definiens (no longer available) and Visiopharm. But now we have over 50 users per month working on Halo and the other platforms have been virtually shut down. Halo is very easy to get up and running - within a 2 hour session we can get a new user started with their own classification and cell counting application. Most users run a batch analysis overnight and collect and review their results in the morning. The team at Indica Labs are quick to respond when we have a challenging analysis project - they will WebEx in and help optimize the parameters. They have the experience (and courage) to tell us if the staining is just not suitable or a more complex classifier is required."
With unmatched ease-of-use, powerful analytic capabilities, and ultra-fast processing speeds, Laboratories around the world depend on HALO® to achieve high-throughput, accurate analysis of their digital pathology.
IMAGE ANALYSIS SIMPLIFIED
Spend less time learning software and more time analyzing data. HALO’s analysis tuning is fast and easy for experts and novices alike, without sacrificing data quality. No need to “build” analysis algorithms from scratch. HALO’s flexible, purpose-built modules provide quick, quantitative results in oncology, neuroscience, metabolism, toxicological pathology, and more.
ACCELERATE YOUR ANALYSIS
Digital slides are large and bog down conventional analysis systems. HALO’s parallel processing technology and optimized algorithms yield up to four times the analysis rate of competitive solutions using the same standard hardware. Organizations with greater throughput demands can couple HALO with our performance boosting analysis clusters.
EASILY EXPLORE CELLULAR DATA
HALO reports morphological and multiplexed expression data on a cell-by-cell basis across entire tissue sections and maintains an interactive link between cell data and cell image. Click on any cell in the image and immediately see analysis outputs for that specific cell. Sorting and filtering capabilities allow the user to mine millions of cells while visually assessing corresponding cell populations. For example, sort cells according to biomarker intensity and immediately locate cells with highest intensity in the image. Just imagine the endless possibilities.
GROW WITH HALO
HALO offers a modular platform that can expand with your needs. Start with a few modules, and add more as your needs change. Use HALO on a single workstation or ramp up to a server-based license for your entire group. HALO is flexible enough for any budget.