Scale-up Services Products & Reviews

Twin-screw extruders are well-established and used in a wide variety of food, polymer, and pharmaceutical applications to efficiently develop and produce high-quality products using a continuous process.  The modularity of the Thermo Scientific™ Process 11 Twin-screw extrusion equipment provides great flexibility in designing a process to accomplish your food process development goals.

CytoPak™ GMP Human IL-2 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, allowing direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.

ActiveMax® Streptavidin μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface. Streptavidin is a tetrameric protein providing 4 high-affinity biotin binding sites, which make it possible to fast prepare and customize your own sterile protein/antibody coupled beads for cell based assay, cell sorting, cell therapy process development and manufacturing use.

CytoPak™ GMP Human IL-7 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, enabling direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine. IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells.

GMP ActiveMax® Human T Cell Activation/Expansion CD3/CD28 Beads are 5.5 μm magnetic beads coated with GMP-grade CD3/CD28 antibodies, mimicking APC stimulation. Manufactured in a GMP-compliant, animal-free process, they enable in vitro isolation, stimulation, and expansion of T cells (CD3+, CD4+, CD8+, PBMC) for clinical and preclinical research.

ACRO offers two GMP-grade DLL4 proteins, GMP-DL4H27 (Flagship Product) and GMP-DL4H28 (Complementary Product), designed for iPSC cell culture and differentiation applications. While both proteins undergo similar manufacturing processes with minor procedural variations, they are strategically positioned to address distinct user needs.

Recombinant IL-2 is widely used in cell culture for the expansion of T cells. In cell culture, IL-2 is a frequently used cytokine for the proliferation, differentiation, and increased antibody secretion of B cells as they transform into plasma cells in vitro.

GMP Human Laminin 521 Protein supports feeder-free PSC culture, maintaining growth and stemness without differentiation for over 10 passages. It’s produced in a GMP-compliant, animal-free process with strict QC testing to ensure quality. Designed for clinical research, it enables a seamless transition from preclinical studies to cell therapy applications.

Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseasesreticulum. The dominant mechanism of IL-15 action is known as transpresentation.GMP IL-7 and GMP IL-15 are commonly used in combination for ex vivo expansion of T cells for cellular therapies.

Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa‑18 kDa Th2 cytokine that shows pleiotropic effects during immune responses.Due to its role in the differentiation of certain immune cell types, IL-4 is commonly used in combination with other growth factors to transform induced pluripotent stem cells into dendritic cells in high numbers.